Why the study?
Does two-dimensional speckle tracking echocardiography improve the noninvasive detection of acute cardiac transplant rejection compared to traditional markers of systolic function?
Does two-dimensional speckle tracking echocardiography improve the noninvasive detection of acute cardiac transplant rejection compared to traditional markers of systolic function?
Two-dimensional speckle tracking echocardiography may offer advantages over traditional systolic function markers in the noninvasive detection and management of acute cardiac transplant rejection.
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Does not yet support incorporating strain imaging into rejection surveillance; leaves open its advantage over traditional systolic markers.
A 44-year-old woman, who had undergone orthotopic cardiac transplantation in 1999, presented acute allograft rejection 4 months after childbirth. Analysis of myocardial deformation by speckle tracking echocardiography showed, in contrast with traditional markers of systolic function, a strong reduction of left ventricular strain, which recovered, together with rejection, under pharmacological treatment. This case documents the potential advantages of speckle tracking echocardiography in the noninvasive management of transplant recipients.
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Lisi et al. (2012) studied this question.
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