Population
Rat aortic rings, pig coronary artery rings, human coronary artery rings, and isolated Langendorff rat heart…
Design
Preclinical
Authors
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Amlodipine shows vasodilatory effects in arterial models; leaves open translation to human coronary therapy.
Amlodipine acts as a potent vasodilator with a slow onset and long-lasting effect across various mammalian vascular and cardiac models.
Matlib et al. (1988) studied this question.
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