Key result
Three hybridoma clones capable of secreting IgG1 kappa chain monoclonal antibodies against epitopes of poliovirus type 1 with good stability and no cross-reactivity were successfully produced.
Why the study?
Poliomyelitis remains a major public health problem in developing countries, signifying the need for extensive diagnostic and prevention research.
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The study successfully produced and characterized stable, specific IgG1 monoclonal antibodies against poliovirus type 1 with potential diagnostic and research applications.
Background and Objectives: Poliomyelitis remains a major public health problem in developing countries, which signify the need for extensive diagnostic and prevention research. The aim of the present study was to design monoclonal antibodies (MAbs) against poliovirus type I with biomedical, diagnostic and therapeutic applications.
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Soleimani et al. (2019) studied Poliovirus Type 1. Monoclonal antibodies against poliovirus type 1 was evaluated on Production and characterization of neutralizing MAbs against PV1. Three hybridoma clones capable of secreting IgG1 kappa chain monoclonal antibodies against epitopes of poliovirus type 1 with good stability and no cross-reactivity were successfully produced.
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