May 1, 1968The Journal of PhysiologyOpen Access

The effect of oestrogen and progesterone on the pressor action of angiotensin in the rat

Q: What is the clinical evidence from this study?

Study design: Other. Intervention: Oestrogen and progesterone vs. Different stages of oestrous cycle / untreated. Primary outcome: Pressor responses to angiotensin.

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Key result

Pregnancy, pseudopregnancy, and progesterone treatment diminished the pressor response to angiotensin in rats, whereas oestrogen had no effect.

Authors

EHE. S. G. Hettiaratchi MPMary PickfordWestern General Hospital

Discussion

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Implication

Does not guide human pregnancy care; leaves open progesterone's contribution to gestational vascular adaptation.

PICO

Population

Female rats evaluated during different stages of the oestrous cycle, pregnancy, pseudopregnancy, and following oestrogen and progesterone treatment.

Intervention / Comparator

Oestrogen and progesterone vs Different stages of oestrous cycle / untreated

Primary Outcome

Pressor responses to angiotensin

Cite This Study

Hettiaratchi et al. (1968) studied this question. Oestrogen and progesterone vs. Different stages of oestrous cycle / untreated was evaluated on Pressor responses to angiotensin. Pregnancy, pseudopregnancy, and progesterone treatment diminished the pressor response to angiotensin in rats, whereas oestrogen had no effect.

synapsesocial.com/papers/6a8f8a2ff859b924fb3ecdc6 https://doi.org/10.1113/jphysiol.1968.sp008517

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The effect of oestrogen and progesterone on the pressor action of angiotensin in the rat

Discussion

Member takes

Implication

PICO

Cite This Study

The effect of oestrogen and progesterone on the pressor action of angiotensin in the rat

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider