Why the study?
Does plasma pindolol concentration correlate with blood pressure reduction in hypertensive patients?
Population
15 previously untreated hypertensive patients, and a separate cohort of 99 hypertensive outpatients
Design
Cohort
Follow-up
8 hours for the single-dose study
Authors
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Pindolol plasma levels may predict BP response independent of renin/noradrenaline; hypothesis-generating and should not yet change practice.
Does plasma pindolol concentration correlate with blood pressure reduction in hypertensive patients?
The blood pressure lowering effect of pindolol correlates with its plasma concentration but is independent of changes in plasma renin or noradrenaline levels.
Anavekar et al. (1975) studied this question.
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