Why the study?
Does pindolol reduce blood pressure and plasma renin activity in hypertensive patients?
Does pindolol reduce blood pressure and plasma renin activity in hypertensive patients?
Low doses of pindolol (10-15 mg daily) are sufficient for mild essential hypertension, as higher doses may paradoxically increase blood pressure and renin activity.
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Pindolol effect may wane by month 3 in half of patients; leaves open optimal long-term dosing in hypertension.
Fyhrquist et al. (1977) studied this question.
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