Why the study?
Do inhaled anesthetics alter the determinants of coronary collateral blood flow in a dog model of coronary occlusion?
Population
12 dogs studied 4-5 weeks after ameroid constrictor implantation
Design
Preclinical
Authors
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May alter coronary collateral flow in experimental occlusion; leaves open relevance to anesthetic choice in patients with CAD.
Do inhaled anesthetics alter the determinants of coronary collateral blood flow in a dog model of coronary occlusion?
Inhaled anesthetics differentially affect segmental resistance and pressure in the coronary circulation, with desflurane decreasing retrograde collateral flow.
Mignella et al. (1995) studied this question.
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