Why the study?
Does captopril reduce blood pressure reactivity to psychological stressors in normotensive and hypertensive men?
Population
46 men (25 normotensive and 21 hypertensive) hospitalized in a clinical research center
Comparison
Captopril 25 mg b.i.d. for 4 days vs Placebo for 4 days
Design
RCT, double-blind
Follow-up
4 days per treatment period
Authors
Loading...
Captopril does not blunt BP reactivity to psychological stressors; confirms dissociation from resting BP reduction in this RCT.
Does captopril reduce blood pressure reactivity to psychological stressors in normotensive and hypertensive men?
Short-term captopril therapy lowers resting blood pressure but does not blunt blood pressure reactivity to acute psychological stressors in men.
Dimsdale et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: