Why the study?
Does captopril alter autonomic reflex functions in patients with essential hypertension?
Population
15 patients with essential hypertension
Comparison
Captopril for 3 weeks vs Baseline (before treatment)
Design
Cohort
Follow-up
3 weeks
Authors
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Captopril may enhance parasympathetic tone in hypertension without reflex impairment; supports autonomic research but should not yet change practice.
Does captopril alter autonomic reflex functions in patients with essential hypertension?
Captopril lowers blood pressure and resting heart rate in hypertensive patients while increasing parasympathetic tone, without impairing sympathetic or baroreceptor reflexes.
Sturani et al. (1982) studied this question.
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