Why the study?
What is the occurrence and duration of the poliomyelitis virus carrier state in familial associates of recognized cases?
Population
Familial associates of recognized cases of poliomyelitis (members of four families)
Design
Cohort
Follow-up
over 2 months
Authors
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May inform contact precautions in polio outbreaks; leaves open age-specific shedding dynamics for prospective validation.
What is the occurrence and duration of the poliomyelitis virus carrier state in familial associates of recognized cases?
Poliomyelitis virus can persist in the stools of familial contacts for up to 4-5 weeks, with children more likely to maintain the virus, suggesting rapid simultaneous infection from a common source.
Brown et al. (1948) studied this question.
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