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September 8, 1945JAMA

Rapid Development of Carrier State and Detection of Poliomyelitis Virus

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Key result

Poliomyelitis virus can be detected in the stools for weeks to months and in the oropharynx in approximately 50% of cases within a few days of paralysis onset.

Population

Patients with poliomyelitis

Design

Other

Authors

GBGordon C. BrownUniversity of Oxford

Discussion

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Implication

Highlights extended fecal shedding for infection control; leaves open optimal testing strategies in post-eradication settings.

Structured PICO

P
Population
Patients with poliomyelitis
O
Outcome
Detection of poliomyelitis virus in stools and oropharynx

The text discusses the timeline and locations for detecting poliomyelitis virus in infected patients.

Cite This Study

Gordon C. Brown (1945) studied Poliomyelitis. Poliomyelitis virus can be detected in the stools for weeks to months and in the oropharynx in approximately 50% of cases within a few days of paralysis onset.

synapsesocial.com/papers/6a93261d178cd16b0f58b84fhttps://doi.org/10.1001/jama.1945.02860360023006
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1CARRIAGE OF THE VIRUS OF POLIOMYELITIS, WITH SUBSEQUENT DEVELOPMENT OF THE INFECTION1917 · 35 citations
  2. 2PERSISTENCE OF VIRUS EXCRETION IN THE STOOLS OF POLIOMYELITIS PATIENTS1944 · 15 citations
  3. 3DETECTION OF THE VIRUS OF POLIOMYELITIS IN THE NOSE AND THROAT AND GASTRO-INTESTINAL TRACT OF HUMAN BEINGS AND MONKEYS1939 · 44 citations
  4. 4Poliomyelitis Virus in the Human Oro-pharynx.1944 · 13 citations
  5. 5NEUTRALIZATION OF THE VIRUS OF POLIOMYELITIS BY NASAL WASHINGS1917 · 32 citations