Population
1-yr old mice and suckling mice
Comparison
Coxsackie A9 virus, Strain 13 infection vs Comparison between 1-yr old mice and suckling mice
Design
Preclinical
Authors
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Age-dependent tropism shift in Coxsackie A9 mouse model; hypothesis-generating for human age-specific viral myocarditis risk.
The study demonstrates an age-dependent differential susceptibility of striated muscle and heart tissue to Coxsackie A9 virus in mice.
Lerner et al. (1962) studied this question.
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