Why the study?
Does 8-bromo-cyclic GMP inhibit basal calcium channel currents in embryonic chick ventricular myocytes?
Does 8-bromo-cyclic GMP inhibit basal calcium channel currents in embryonic chick ventricular myocytes?
Cyclic GMP can inhibit basal calcium channel currents in embryonic chick heart cells through a cyclic AMP-independent mechanism.
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Demonstrates cGMP-mediated calcium current suppression in chick myocytes; leaves open relevance to human cardiac electrophysiology.
Wahler et al. (1990) studied this question.
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