Why the study?
Does empirical chronic oral amiodarone therapy reduce the recurrence of VT/VF in patients with sustained ventricular tachyarrhythmia and structural heart disease?
Population
129 patients with sustained ventricular tachyarrhythmia (VT/VF) and structural heart disease
Comparison
Empirical chronic oral amiodarone therapy vs Class I antiarrhythmic drugs monitored by…
Design
Cohort
Follow-up
up to 36 months
Authors
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Amiodarone tolerance may be linked to lower VT/VF recurrence; leaves open randomized confirmation before changing practice.
Does empirical chronic oral amiodarone therapy reduce the recurrence of VT/VF in patients with sustained ventricular tachyarrhythmia and structural heart disease?
Empirical amiodarone therapy provides substantial long-term benefit comparable to EPS/Holter-guided class I drugs for suppressing VT/VF recurrence in high-risk patients with structural heart disease.
Aiba et al. (2002) studied this question.
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