Why the study?
Does captopril reduce blood pressure in normotensive healthy subjects and patients with essential hypertension?
Does captopril reduce blood pressure in normotensive healthy subjects and patients with essential hypertension?
Captopril significantly lowers blood pressure in both normotensive and hypertensive individuals, highlighting the renin system's role in blood pressure regulation.
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Captopril's BP-lowering effect in normotensives varies with sodium intake; leaves open its role in essential hypertension.
MacGregor et al. (1983) studied this question.
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