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The study demonstrates antigenic similarities between encephalitogenic factor and measles virus, potentially explaining elevated measles antibodies in multiple sclerosis.
A combination of affinity chromatography with the macrophage electrophoretic migration (MEM) test has been used to study the antigenic similarities between encephalitogenic factor (EF) and measles virus. These have determinant(s) sufficiently closely related to account for the elevated level of circulating antibody to measles in multiple sclerosis.
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McDermott et al. (1974) studied this question.
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