Why the study?
Is the angiotensin-converting enzyme insertion-deletion polymorphism associated with pre-eclampsia in pregnant women?
Population
155 pregnant women, comprising 72 with pre-eclampsia and 83 normotensive pregnant women. Fetal samples were…
Comparison
Angiotensin-converting enzyme gene… vs ID and II genotypes
Design
Case-control
Authors
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No association in this case-control study; leaves open whether ACE I/D polymorphism influences pre-eclampsia risk in other settings.
Is the angiotensin-converting enzyme insertion-deletion polymorphism associated with pre-eclampsia in pregnant women?
There is no significant association between the insertion-deletion polymorphism in the angiotensin-converting enzyme gene and the development of pre-eclampsia.
Morgan et al. (1999) studied this question.
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