Population
Normotensive and one-kidney, one-clip Goldblatt hypertensive rats anesthetized with sodium pentobarbital
Comparison
Exposure of cremaster muscle arterioles to… vs Normotensive (NT) rats
Design
Preclinical
Authors
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May guide mechanistic studies of calcium entry in hypertension models; leaves open clinical translation.
In a rat model of renovascular hypertension, increased arteriolar reactivity appears to involve an increase in receptor-mediated entry of extracellular calcium into vascular smooth muscle.
Joshua et al. (1987) studied this question.
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