Population
Guinea pig isolated papillary muscles
Comparison
Propofol at concentrations producing… vs Enflurane and ryanodine at concentrations…
Design
Preclinical
Authors
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Propofol's lack of SR effect in guinea pigs warrants caution extrapolating to patients; leaves open clinical relevance in humans.
Propofol does not appear to impair sarcoplasmic reticulum function in guinea pig myocardium, unlike enflurane.
Puttick et al. (1993) studied this question.
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