Why the study?
Does epidural anaesthesia alter the pituitary-adrenal cortisol response compared to general anaesthesia in patients undergoing pelvic surgery?
Population
9 patients undergoing pelvic surgery
Comparison
Epidural anaesthesia vs General anaesthesia
Design
Cohort
Authors
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Blunted cortisol response under epidural anaesthesia warrants no practice change; hypothesis-generating for outcomes in pelvic surgery, needing RCTs.
Does epidural anaesthesia alter the pituitary-adrenal cortisol response compared to general anaesthesia in patients undergoing pelvic surgery?
Epidural anaesthesia blunts the pituitary-adrenal cortisol response to pelvic surgery compared to general anaesthesia, without causing adverse clinical problems.
Cosgrove et al. (1974) studied this question.
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