Population
Rat soleus (SOL) and plantaris (PLAN) muscles
Comparison
28 days of hindlimb suspension vs Control rats
Design
Preclinical
Follow-up
28 days
Authors
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Rat soleus speeds via myosin shifts after suspension; hypothesis-generating for human disuse without practice implications.
Hindlimb suspension in rats induces significant speeding of soleus contractile properties, likely driven by a shift toward faster myosin isoforms with higher ATPase activity.
Diffee et al. (1991) studied this question.
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