Population
Bovine aortic endothelial cells
Comparison
Calmodulin added to the patch pipette at various… vs Control or intracellular Ca2+ buffered to 1 nM…
Design
Preclinical
Authors
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Hypothesis-generating for calmodulin regulation of endothelial calcium entry; requires validation in human models before any clinical consideration.
Calmodulin inhibits thapsigargin-induced calcium influx in vascular endothelium, indicating a regulatory role in store-operated calcium entry.
Luis Vaca (1996) studied this question.
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