Population
Cultured vascular smooth muscle (VSM) cells (A7r5 cell line)
Design
Preclinical
Authors
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CMZ's direct L-type Ca channel blockade may confound CaM inhibitor interpretations in vascular studies; leaves open in vivo relevance.
Calmidazolium directly blocks L-type Ca2+ channels in vascular smooth muscle cells independently of CaM-dependent pathways.
Sunagawa et al. (1999) studied this question.
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