Why the study?
Does nisoldipine lower blood pressure and alter central haemodynamics in patients with essential hypertension?
Population
19 patients with essential hypertension
Design
Cohort
Follow-up
1 year
Authors
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Supports nisoldipine-associated BP reduction via TPR lowering in hypertension; leaves open randomized confirmation of long-term hemodynamic stability.
Does nisoldipine lower blood pressure and alter central haemodynamics in patients with essential hypertension?
Nisoldipine effectively lowers blood pressure in essential hypertension primarily by reducing total peripheral resistance, with initial reflex tachycardia resolving during long-term therapy.
Omvik et al. (1988) studied this question.
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