Why the study?
Does intracoronary bradykinin affect coronary blood flow velocity and regional myocardial function in conscious dogs?
Population
11 conscious dogs chronically instrumented with a left ventricular micromanometer, a circumflex coronary…
Comparison
Intracoronary bradykinin alone or with… vs Baseline (absence of systemic hemodynamic changes)
Design
Preclinical
Authors
Loading...
Extends bradykinin coronary effects to conscious models without altering function; leaves open human translation.
Does intracoronary bradykinin affect coronary blood flow velocity and regional myocardial function in conscious dogs?
In conscious dogs, the vasodilator effect of intracoronary bradykinin, even when enhanced by enalaprilat, increases coronary blood flow and end-diastolic wall thickness without altering regional myocardial systolic function.
Hoüel et al. (1997) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: