Population
Freshly isolated hearts of fetal mice of gestational ages ranging between 12 and 22 days (term)
Design
Preclinical
Authors
Loading...
Should not guide fetal or neonatal drug use in humans; leaves open translation of sequential receptor maturation to other species.
The study demonstrates that fetal mouse hearts develop responsiveness to different cardioactive drugs at distinct gestational stages, reflecting the sequential maturation of specific cardiac receptors and innervation.
Wildenthal et al. (1973) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: