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May 9, 2007Echocardiography

Noninvasive Assessment of Coronary Flow Reserve in the Left Anterior Descending Artery by Transthoracic Echocardiography before and after Stenting

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Why the study?

Does percutaneous angioplasty with stenting improve coronary flow reserve in patients with significant isolated LAD stenosis?

Population

36 patients with significant isolated left anterior descending artery stenosis identified by coronary…

Comparison

Percutaneous angioplasty with stenting vs Baseline (before stenting)

Design

Cohort

Follow-up

Immediately after stenting

Authors

ECElie ChammasUniversity of BalamandCDChadi DibHeart Hospital Baylor PlanoMRMaya RahhalLebanese University

Discussion

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Overview

TTDE CFR assessment may aid noninvasive LAD stenosis evaluation in select patients; leaves open need for prospective validation.

Structured PICO

Does percutaneous angioplasty with stenting improve coronary flow reserve in patients with significant isolated LAD stenosis?

P
Population
36 patients with significant isolated left anterior descending artery (LAD) stenosis (70-90%) identified by coronary angiography
I
Intervention
Percutaneous angioplasty with stenting
C
Comparator
Baseline (before stenting)
O
Outcome
Coronary flow reserve (CFR) in the mid-to-distal LAD measured by transthoracic Doppler echocardiographysurrogate

Transthoracic Doppler echocardiography can noninvasively detect the early recovery of coronary flow reserve and microvascular tone immediately after LAD stenting.

Limitations

  • Small sample size
  • Lack of long-term follow-up

Cite This Study

Chammas et al. (2007) studied this question.

synapsesocial.com/papers/6a9263eefd03cddea1963057https://doi.org/10.1111/j.1540-8175.2007.00478.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Noninvasive Assessment of Significant Left Anterior Descending Coronary Artery Stenosis by Coronary Flow Velocity Reserve With Transthoracic Color Doppler Echocardiography1998 · 404 citations
  2. 2Coronary Physiology Revisited2000 · 237 citations
  3. 3A Preliminary Report Comparing Magnetic Resonance Coronary Angiography with Conventional Angiography1993 · 546 citations
  4. 4Value of Electron-Beam Computed Tomography for the Noninvasive Detection of High-Grade Coronary-Artery Stenoses and Occlusions1998 · 385 citations