February 1, 1983The Journal of Cell BiologyOpen Access

Evidence for actin involvement in cardiac Z-lines and Z-line analogues.

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Population

Canine and feline cardiac muscle fibers (Z-lines and Z-rods)

Comparison

Digestion with Ca2+-activated protease and heavy… vs Before digestion (untreated)

Design

Preclinical

Authors

MYM. YamaguchiUniversity of Fukui RRR. RobsonUniversity of Arizona MSMarvin H. StromerIowa State University

Discussion

Member takes

Implication

Informs sarcomere architecture models; extends filament continuity concepts but remains preclinical.

Structured PICO

Population

Canine and feline cardiac muscle fibers (Z-lines and Z-rods)

Intervention

Digestion with Ca2+-activated protease (CAF) and heavy meromyosin binding

Comparator

Before digestion (untreated)

Outcome

Structural composition and filament identification in Z-lines and Z-rodssurrogate

This basic science study demonstrates that actin filaments are integral components of cardiac Z-lines and Z-rods, overlapping to determine their dimensions.

Cite This Study

Yamaguchi et al. (1983) studied this question.

synapsesocial.com/papers/6a9285c5fa60aefc093aaffb https://doi.org/10.1083/jcb.96.2.435

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Ask AI

Bookmark

Evidence for actin involvement in cardiac Z-lines and Z-line analogues.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Evidence for actin involvement in cardiac Z-lines and Z-line analogues.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider