Why the study?
Does a bolus dose of remifentanil cause severe bradycardia and hypotension in patients undergoing CABG surgery?
Population
30 patients undergoing coronary artery bypass graft (CABG) surgery anesthetized with remifentanil.
Design
Case_series
Follow-up
Intraoperative
Authors
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Rapid remifentanil boluses warrant caution in CABG anesthesia; this case series leaves open optimal dosing and mitigation strategies.
Does a bolus dose of remifentanil cause severe bradycardia and hypotension in patients undergoing CABG surgery?
A 1 microgram/kg bolus of remifentanil administered rapidly via syringe pump during CABG anesthesia can cause severe, vagally-mediated bradycardia and hypotension.
DeSouza et al. (1997) studied this question.
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