Key result
Monthly supplementation with 60,000 IU of oral vitamin D3 for 16 weeks significantly improved flow-mediated dilation compared to placebo (1.8% vs -1.3% change) in overweight African-American adults.
Why the study?
Does oral vitamin D3 supplementation improve flow-mediated dilation in overweight African-American adults?
RCT (n=57)
Double-blind
randomized
Does oral vitamin D3 supplementation improve flow-mediated dilation in overweight African-American adults?
Absolute Event Rate: 1.8% vs -1.3%
Monthly high-dose oral vitamin D3 supplementation for 16 weeks improves vascular endothelial function, as measured by flow-mediated dilation, in overweight African-American adults.
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Supports vitamin D3 supplementation for endothelial function in overweight African-American adults; extends randomized evidence to this high-risk group.
Harris et al. (2011) conducted an RCT in Overweight (n=57). Vitamin D3 vs. Placebo was evaluated on Flow-mediated dilation (FMD). Monthly supplementation with 60,000 IU of oral vitamin D3 for 16 weeks significantly improved flow-mediated dilation compared to placebo (1.8% vs -1.3% change) in overweight African-American adults.
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