Key result
No inactive renin was found in the venous effluent of perfused rat kidneys before or after isoprenaline stimulation, suggesting an extrarenal source for inactive renin.
The absence of inactive renin in the venous effluent of perfused rat kidneys suggests an extrarenal source for inactive renin.
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Questions renal origin of inactive renin in rats; hypothesis-generating for extrarenal sources in humans.
Vandongen et al. (1977) studied this question. Isoprenaline stimulation vs. Before stimulation was evaluated on Presence of inactive renin in blood-free venous effluent of the perfused rat kidney. No inactive renin was found in the venous effluent of perfused rat kidneys before or after isoprenaline stimulation, suggesting an extrarenal source for inactive renin.
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