Key result
Cardiac catabolic factors secreted by porcine heart valves and aorta stimulate the degradation of cartilage matrix and induce the release of chondroitin sulfate and hydroxyproline.
Answers are grounded in this paper and cite their sources.
Cultures of porcine heart valves and aorta secrete a factor that stimulates the degradation of cartilage matrix in a fashion similar to that displayed by synovial catabolin. The heart valve factor also induces the release of chondroitin sulfate and hydroxyproline from isolated heart valve cultures. The present observations support the hypothesis that tissues producing catabolic factors (catabolins) may well be responsive to them and that these messengers may play a role in the cellular regulation of the degradation of intercellular macromolecules.
No takes yet. Share an insight, caveat, or question.
Decker et al. (1982) studied Heart valve intercellular matrix degradation. Cardiac catabolic factors was evaluated on Degradation of cartilage matrix and release of chondroitin sulfate and hydroxyproline. Cardiac catabolic factors secreted by porcine heart valves and aorta stimulate the degradation of cartilage matrix and induce the release of chondroitin sulfate and hydroxyproline.
Synapse has enriched 10 related papers. Consider them for comparative context: