Why the study?
Does premedication with hydroxyzine and scopolamine prevent wakefulness during high-dose fentanyl anesthesia induction in patients undergoing cardiovascular surgery?
Observational (n=36)
No
Does premedication with hydroxyzine and scopolamine prevent wakefulness during high-dose fentanyl anesthesia induction in patients undergoing cardiovascular surgery?
Absolute Event Rate: 0% vs 63.6%
Adequate premedication with hydroxyzine and scopolamine effectively prevents wakefulness and provides a smoother induction without significant hemodynamic complications during high-dose fentanyl anesthesia for cardiovascular surgery.
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Watanabe et al. (1986) conducted an observational in Elective cardiac surgery (n=36). Premedication with hydroxyzine and scopolamine (with or without pethidine) vs. Premedication with morphine and scopolamine was evaluated on Wakefulness (response to verbal commands using isolated forearm technique) during induction with high-dose fentanyl.
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