Key result
24-hour sleep deprivation in 9 healthy men demonstrated a persistent slight decrease in nighttime plasma noradrenaline concentrations, suggesting an underlying biological clock.
Why the study?
Does sleep deprivation obliterate the circadian rhythm of plasma noradrenaline in healthy men?
Observational (n=9)
No
Does sleep deprivation obliterate the circadian rhythm of plasma noradrenaline in healthy men?
The circadian rhythm of plasma noradrenaline may be partially driven by an endogenous biological clock independent of sleep and posture.
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May support endogenous clock for noradrenaline rhythm in healthy men; leaves open relevance to cardiovascular patients.
Candito et al. (1992) conducted an observational in Healthy (n=9). Sleep deprivation was evaluated on Plasma noradrenaline (NA) concentration over 24 hours. 24-hour sleep deprivation in 9 healthy men demonstrated a persistent slight decrease in nighttime plasma noradrenaline concentrations, suggesting an underlying biological clock.
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