Why the study?
Does the combination of low-dose heparin and graded compression stockings prevent postoperative thromboembolism better than heparin alone in patients undergoing elective major abdominal surgery?
Population
n=176 patients scheduled for elective major abdominal surgery
Comparison
Low-dose heparin supplemented with graded… vs Low-dose heparin alone
Design
RCT, randomized to two prophylactic regimens
Authors
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Supports adding graded compression stockings to heparin for VTE prophylaxis in elective major abdominal surgery; confirms benefit of combined mechanical-pharmacologic prevention in RCT.
Does the combination of low-dose heparin and graded compression stockings prevent postoperative thromboembolism better than heparin alone in patients undergoing elective major abdominal surgery?
Adding graded compression stockings to low-dose heparin significantly reduces the risk of postoperative thromboembolism in patients undergoing major abdominal surgery compared to heparin alone.
Thorup et al. (1985) studied this question.
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