February 1, 1981Journal of Interferon Research
Partial Mapping of Ten Genes of the Human Interferon- α Family
Key result
Human interferon-alpha genes form a family of at least 9 to 10 distinct members, with at least three arranged in tandem and the three sequenced thus far lacking introns.
Population
Human Interferon-alpha genes
Design
Preclinical
Authors
Discussion
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Member takes
Implication
No immediate clinical implications; leaves open functional roles of distinct interferon-alpha genes in disease.
Structured PICO
P
Population
Human Interferon-alpha genes
I
Intervention
Sequence analysis and gene mapping
O
Outcome
Identification and mapping of gene family members and structure
The study maps the human interferon-alpha gene family, identifying at least 9-10 members and revealing that the sequenced genes lack introns.
Cite This Study
Nagata et al. (1981) studied this question. Human interferon-alpha genes form a family of at least 9 to 10 distinct members, with at least three arranged in tandem and the three sequenced thus far lacking introns.