Why the study?
Does captopril reduce plasma hBNP-li levels in male patients with mild to moderate congestive heart failure?
Does captopril reduce plasma hBNP-li levels in male patients with mild to moderate congestive heart failure?
Acute ACE inhibition with captopril in heart failure patients significantly reduces plasma hBNP and ANP levels, likely due to changes in intra-cardiac volume and pressure.
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Supports acute ACEI use to lower natriuretic peptides in mild-moderate HF; confirms hemodynamic effects in this population.
Lang et al. (1992) studied this question.
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