Key result
Despite no direct trials in cardiac surgery, the 15-20% incidence of postoperative DVT and 0.5-4% incidence of PE supports recommending routine heparin prophylaxis until discharge.
Why the study?
Does prophylactic postoperative low molecular weight heparin or unfractionated heparin reduce the incidence of deep vein thromboses and pulmonary emboli in patients post-cardiac surgery?
Population
Patients post-cardiac surgery
Design
Systematic_review
Authors
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Supports routine heparin prophylaxis until discharge after cardiac surgery; extends non-cardiac surgery evidence while underscoring need for direct RCTs.
Does prophylactic postoperative low molecular weight heparin or unfractionated heparin reduce the incidence of deep vein thromboses and pulmonary emboli in patients post-cardiac surgery?
Heparin prophylaxis is recommended for all patients post-cardiac surgery starting the day after surgery to prevent DVT and PE, based on extrapolated evidence from non-cardiac surgery.
V. Close (2006) conducted a review in Post-cardiac surgery. Prophylactic postoperative low molecular weight heparin (LMWH) or unfractionated heparin was evaluated on Incidence of deep vein thromboses (DVTs) and pulmonary emboli (PEs). Despite no direct trials in cardiac surgery, the 15-20% incidence of postoperative DVT and 0.5-4% incidence of PE supports recommending routine heparin prophylaxis until discharge.
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