Key result
Four immunoassay methods (two RIAs, two ELISAs) for measuring serum acid-labile subunit were highly correlated across 125 sera from various patient groups.
Why the study?
Do different immunoassay methods (RIAs and ELISAs) yield correlated measurements of serum acid-labile subunit (ALS)?
Observational (n=125)
Do different immunoassay methods (RIAs and ELISAs) yield correlated measurements of serum acid-labile subunit (ALS)?
A variety of immunoassay formats and reagents can yield highly correlated and clinically useful serum ALS values.
No takes yet. Share an insight, caveat, or question.
Correlated ALS values across immunoassays support method comparability in research; leaves open clinical standardization.
Baxter et al. (2000) conducted an observational in Various patient groups (healthy, growth hormone-deficient, acromegaly, pregnant, chronic renal failure) (n=125). Four immunoassay methods (two RIAs, two ELISAs) was evaluated on Correlation of ALS measurements among four immunoassay methods. Four immunoassay methods (two RIAs, two ELISAs) for measuring serum acid-labile subunit were highly correlated across 125 sera from various patient groups.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: