Key result
Total serum ALS levels measured by a novel ELISA were 16.7 mg/L in normal subjects, 28.3 mg/L in acromegalic patients, and 9.5 mg/L in GH-deficient adults.
Population
74 adults, including 22 normal subjects, 20 acromegalic patients, and 32 GH-deficient adults.
Design
Cross-sectional
Authors
Loading...
Novel ALS ELISA distinguishes GH states; leaves open diagnostic utility pending prospective validation.
Observational (n=74)
The development of a noncompetitive ALS ELISA allows for the measurement of total and uncomplexed ALS levels, demonstrating distinct levels in normal, acromegalic, and GH-deficient individuals.
Khosravi et al. (1997) conducted an observational in Acromegaly and Growth Hormone Deficiency (n=74). Serum ALS measurement vs. Normal subjects was evaluated on Total ALS levels. Total serum ALS levels measured by a novel ELISA were 16.7 mg/L in normal subjects, 28.3 mg/L in acromegalic patients, and 9.5 mg/L in GH-deficient adults.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: