Key result
FMDV serotype A potential vaccine strain BAN/CH/Sa-304/2016 revealed antigenic heterogeneity with Indian strain IND40/00, featuring four amino acid substitutions in the VP1 protein.
The near-complete genome sequence of a potential FMDV serotype A vaccine strain from Bangladesh reveals antigenic differences from the current Indian vaccine strain.
May guide regional FMDV vaccine strain selection; leaves open cross-protection against Indian strains.
The near-complete genome sequence of foot-and-mouth disease virus (FMDV) serotype A potential vaccine strain BAN/CH/Sa-304/2016 is reported here. Its genome revealed antigenic heterogeneity with the current Indian vaccine strain IND40/00, with four amino acid substitutions in antigenically critical sites of the VP1 protein.
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Amin et al. (2019) studied this question. FMDV serotype A potential vaccine strain BAN/CH/Sa-304/2016 revealed antigenic heterogeneity with Indian strain IND40/00, featuring four amino acid substitutions in the VP1 protein.
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