Key result
FMDV serotype A genome from Bangladesh diverges from vaccine strains, indicating transboundary spread.
The complete genome sequence of FMDV serotype A isolate BDSH_01 from Bangladesh reveals sequence divergence from vaccine strains, highlighting its epidemiological and immunological significance.
May warrant updating FMDV A vaccine strains; challenges assumed cross-protection and extends transboundary surveillance needs.
We present the complete genome sequence of foot-and-mouth disease virus serotype A isolate BDSH_01 from Bangladesh. The 8,140-nucleotide genome encodes a 2,333-aa polyprotein with conserved motifs. Phylogenetically, within lineage A/ASIA/G-VII, clustering with recent regional strains indicates transboundary transmission. Sequence divergence from vaccine strains highlights its epidemiological and immunological significance.
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Hayat et al. (2026) studied this question. The complete genome of FMDV serotype A isolate BDSH_01 from Bangladesh shows divergence from vaccine strains, indicating transboundary spread and epidemiological significance.
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