Why the study?
Does intraarterial infusion of isoproterenol alter carbohydrate metabolism in isolated canine hearts?
Population
Isolated, metabolically supported preparations of the canine heart
Design
Preclinical
Authors
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Does not implicate carbohydrate substrates for isoproterenol-driven oxidative metabolism in canine hearts; leaves open primary fuel identification for human translation.
Does intraarterial infusion of isoproterenol alter carbohydrate metabolism in isolated canine hearts?
Isoproterenol-induced increases in oxidative metabolism in the isolated canine heart are not primarily fueled by carbohydrate substrates.
Winterscheid et al. (1963) studied this question.
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