February 1, 1959Experimental Biology and Medicine

Role of Liver and Kidney in Development of Heparin-induced Lipemia Clearing Activity (LCA).,

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Why the study?

Does heparin injection affect lipemia clearing activity in hepatectomized, CCl4-cirrhotic and nephrectomized rats compared to normal controls?

Population

Hepatectomized, CCl4-cirrhotic and nephrectomized rats

Comparison

Heparin injection vs Heparin-injected normal control rats

Design

Preclinical

Authors

PCP. ConstantinidesLouisiana State University YSY. SoJeonbuk National University FJF. R. C. JohnstoneMadigan Army Medical Center

Discussion

Member takes

Implication

Hypothesis-generating for hepatic/renal inactivation of heparin-induced clearing factor in rats; should not yet alter clinical practice.

Structured PICO

Does heparin injection affect lipemia clearing activity in hepatectomized, CCl4-cirrhotic and nephrectomized rats compared to normal controls?

Population

Hepatectomized, CCl4-cirrhotic and nephrectomized rats

Intervention

Heparin injection

Comparator

Heparin-injected normal control rats

Outcome

Lipemia clearing activity when incubated with lipemic plasma in vitrosurrogate

The study provides indirect evidence for a clearing factor inactivating system in the liver and kidney of rats.

Cite This Study

Constantinides et al. (1959) studied this question.

synapsesocial.com/papers/6a9509eda35b9ad7aee622ed https://doi.org/10.3181/00379727-100-24593

View Full Paper

Ask AI

Bookmark

Role of Liver and Kidney in Development of Heparin-induced Lipemia Clearing Activity (LCA).,

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Role of Liver and Kidney in Development of Heparin-induced Lipemia Clearing Activity (LCA).,

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider