Key result
Right intra-atrial injection of phenyl diguanide caused a reflex inhibition of monosynaptic reflexes lasting for several seconds via regions of the brain cephalad to the intercollicular level.
Population
Cats anaesthetized with pentobarbitone sodium
Comparison
Right intra-atrial injection of phenyl diguanide vs Injection of phenyl diguanide close to the…
Design
Preclinical
Authors
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Suggests pulmonary J-receptor modulation of spinal reflexes in animals; leaves open translation to human physiology or clinical relevance.
Stimulation of type J pulmonary endings causes reflex inhibition of monosynaptic reflexes via supraspinal pathways.
Deshpande et al. (1970) studied this question. Right intra-atrial injection of phenyl diguanide vs. Injection close to the aortic valves was evaluated on Depression of monosynaptic reflexes. Right intra-atrial injection of phenyl diguanide caused a reflex inhibition of monosynaptic reflexes lasting for several seconds via regions of the brain cephalad to the intercollicular level.
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