Key result
Pregnancy in women with atrial switch repair for TGA was associated with similar rates of cardiovascular events compared to childless controls (62% vs 53%, P=0.736).
Why the study?
Does pregnancy increase the risk of cardiovascular events in women with atrial switch repair for transposition of the great arteries compared to childless controls?
Population
36 women with atrial switch repair for transposition of the great arteries, including 21 who had pregnancies…
Comparison
Pregnancy (34 pregnancies in 21 women) vs Childless women with the same atrial switch repair
Design
Cohort
Follow-up
Mean 100 months
Authors
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May support pregnancy counseling in TGA atrial switch without excess CV events; leaves open TR progression and needs prospective data.
Cohort (n=36)
No
Does pregnancy increase the risk of cardiovascular events in women with atrial switch repair for transposition of the great arteries compared to childless controls?
Absolute Event Rate: 62% vs 53%
p-value: p=0.736
Pregnancy in women with atrial switch repair for TGA is associated with a similar overall rate of cardiovascular events compared to childless controls, but carries a significantly higher risk of worsening tricuspid regurgitation.
Cataldo et al. (2015) conducted a cohort in Transposition of the great arteries (TGA) with atrial switch repair (n=36). Pregnancy vs. Childless women with the same repair was evaluated on Occurrence of cardiovascular events (p=0.736). Pregnancy in women with atrial switch repair for TGA was associated with similar rates of cardiovascular events compared to childless controls (62% vs 53%, P=0.736).
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