Why the study?
Atrial or arterial switch operations for transposition of the great arteries can complicate physiological adaptation to pregnancy and adversely affect the fetus.
Does the type of surgical correction (atrial vs. arterial switch) for transposition of the great arteries affect obstetric outcomes such as pre-term delivery and small for gestational age?
Population
48 completed pregnancies in 23 women with surgically corrected TGA
Comparison
Atrial switch (38 pregnancies) vs arterial switch operation (10 pregnancies)
Design
Retrospective single tertiary referral centre study
Key result
Atrial switch operations were associated with a significantly higher rate of small for gestational age babies compared to arterial switch operations (66% vs 20%, p=0.013).
Authors
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Supports individualized obstetric planning by TGA repair type; leaves open causality and generalizability in larger cohorts.
Cohort (n=23)
No
Does the type of surgical correction (atrial vs. arterial switch) for transposition of the great arteries affect obstetric outcomes such as pre-term delivery and small for gestational age?
Absolute Event Rate: 66% vs 20%
p-value: p=0.013
Women with surgically corrected TGA are at high risk for obstetric complications, with small for gestational age babies occurring significantly more often following an atrial switch compared to an arterial switch.
Fabre‐Gray et al. (2019) conducted a cohort in Transposition of the great arteries (TGA) (n=23). Atrial switch operation vs. Arterial switch operation was evaluated on Small for gestational age (p=0.013). Atrial switch operations were associated with a significantly higher rate of small for gestational age babies compared to arterial switch operations (66% vs 20%, p=0.013).
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