Population
14-day-old Swiss and young adult Nude (athymic) mice infected with Coxsackievirus B3
Design
Preclinical
Follow-up
up to at least 4 days post-infection
Authors
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Potential leukocyte reservoir after plasma clearance in mice; hypothesis-generating for human CVB3 myocarditis and should not change practice.
Coxsackievirus B3 viremia in mice is primarily in plasma, but mononuclear leukocytes can harbor the virus even after plasma clearance.
Gomez et al. (1980) studied this question.
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