Key result
In high-risk patients with severe aortic stenosis undergoing TAVI, there was no significant difference in 12-month all-cause mortality between women and men (13.1% vs. 25.0%; age-adjusted OR 2.51; p=0.13).
Why the study?
Does gender affect clinical outcomes and quality of life in high-risk patients with severe aortic stenosis undergoing TAVI?
Population
101 consecutive patients with symptomatic severe aortic stenosis and high surgical risk or contraindications…
Comparison
Transcatheter aortic valve implantation in… vs Transcatheter aortic valve implantation in male…
Design
Cohort
Follow-up
12 months
Authors
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No sex difference in post-TAVI mortality supports equitable access; leaves open need for larger prospective studies on subgroups and QoL.
Observational (n=101)
No
Does gender affect clinical outcomes and quality of life in high-risk patients with severe aortic stenosis undergoing TAVI?
Odds Ratio: 2.51 (95% CI 0.87–7.25)
Absolute Event Rate: 13.1% vs 25%
p-value: p=0.13
TAVI is an effective and safe treatment in high-risk patients with severe aortic stenosis, with similar 30-day and 12-month mortality and quality of life improvements regardless of gender.
Bagieński et al. (2017) conducted an observational in Severe aortic stenosis (n=101). Female sex vs. Male sex was evaluated on 12-month all-cause mortality (OR 2.51, 95% CI 0.87-7.25, p=0.13). In high-risk patients with severe aortic stenosis undergoing TAVI, there was no significant difference in 12-month all-cause mortality between women and men (13.1% vs. 25.0%; age-adjusted OR 2.51; p=0.13).
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