Key result
Female sex was associated with a significantly lower 30-day mortality rate compared to male sex following transcatheter aortic valve implantation (OR 0.78; 95% CI 0.64-0.96).
Why the study?
Does female sex improve survival outcomes in patients undergoing TAVI for aortic stenosis?
Population
7,973 patients with aortic stenosis treated with all forms of TAVI, pooled from 14 observational studies
Comparison
Female sex (TAVI in women) vs Male sex (TAVI in men)
Design
Meta-analysis
Follow-up
30 days and during follow-up
Authors
Loading...
May inform sex-specific risk counseling in TAVI; extends meta-analytic evidence on short-term survival differences.
Meta-Analysis (n=7,973)
Does female sex improve survival outcomes in patients undergoing TAVI for aortic stenosis?
Odds Ratio: 0.78 (95% CI 0.64–0.96)
Women undergoing TAVI for aortic stenosis have a significant survival advantage over men at 30 days and during follow-up, despite a higher risk of major vascular complications.
Stangl et al. (2014) conducted a meta-analysis in Aortic stenosis (n=7,973). Female sex vs. Male sex was evaluated on 30-day mortality (OR 0.78, 95% CI 0.64-0.96). Female sex was associated with a significantly lower 30-day mortality rate compared to male sex following transcatheter aortic valve implantation (OR 0.78; 95% CI 0.64-0.96).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: